منابع مشابه
Neo-intimal hyperplasia, diabetes and endovascular injury
Diabetes is a significant major risk factor for peripheral arterial disease (PAD) and critical limb ischaemia (CLI), the latter which is also the most common cause of amputation in these patients. Revascularisation of the lower extremities of such patients is imperative for limb salvage and has become First-line therapy. However, the incidence of restenosis following endovascular stenting is ve...
متن کاملIntimal hyperplasia, vascular modeling, and the restenosis problem.
At the recent Scientific Sessions of the American Heart Association, a plenary session was devoted to the problem of restenosis after percu-taneous transluminal coronary angioplasty.' The panel included five widely recognized and experienced physician scientists who provided critical, comprehensive reviews of the problem. Two of the speakers dealt with the clinical, angiographic, and pathobiolo...
متن کاملAngiogenesis-dependent and independent phases of intimal hyperplasia.
BACKGROUND Neointimal vascular smooth muscle cell (VSMC) proliferation is a primary cause of occlusive vascular disease, including atherosclerosis, restenosis after percutaneous interventions, and bypass graft stenosis. Angiogenesis is implicated in the progression of early atheromatous lesions in animal models, but its role in neointimal VSMC proliferation is undefined. Because percutaneous co...
متن کاملEndothelial implants inhibit intimal hyperplasia after porcine angioplasty.
The perivascular implantation of tissue-engineered endothelial cells around injured arteries offers an opportunity to study fundamental vascular physiology as well as restore and improve tissue function. Cell source is an important issue because the ability to implant either xenogeneic or allogeneic cells would greatly enhance the clinical applications of tissue-engineered grafts. We investigat...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2007
ISSN: 0009-7330,1524-4571
DOI: 10.1161/circresaha.107.160911